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Glucocorticoid, approximate equivalent dose (mg), half-life (biologic) hours. Equivalent anti-inflammatory doses of different oral corticosteroids. This table takes no account of mineralocorticoid effects, nor does it take account of variations. Drug, cortisone, hydrocortisone, prednisone, methylprednisolone, dexamethasone. Equivalent dose, 25, 20, 5, 4, 0. Mineralocorticoid potency, 2+, 2+, 1+. Determine equivalent dosage of corticosteroid. The corticosteroid equivalence calculations are based on old studies comparing the degree of acth. In normal individuals, physiological doses of corticosteroids are equivalent to a dose. Equivalent total daily doses of alternative glucocorticoids to dexamethasone 6 mg daily are methylprednisolone 32 mg and prednisone 40 mg. The target prednisone dose and dividing by 7 or 8 to get an equivalent dexamethasone dose. If daily dose is < 50 mg hydrocortisone or 10mg of prednisolone or equivalent. Doses of glucocorticoids exceeding 30 mg of hydrocortisone or its equivalent. In the airways, resulting in a lower daily dose for equivalent efficacy. Equivalent anti-inflammatory doses of corticosteroids. Mineralocorticoid activity is also described relative to hydrocortisone, and structural modifications to the steroid molecule are
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